Hordenine

Note: This product is not a dietary supplement. This product is for research purposes only and is not intended for consumption.

Hordenine

Hordenine is a substance known primarily for its stimulant effects. In addition, hordenine can also be considered a substance that may have similar effects to nootropics.

Hordenine is also known as:
N,N-dimethyltyramine
Peyocactin
Anhaline
Cactine
Ordenine
Eremursin

Hordenine information

Cas: 6027-23-2
MF: C10H16ClNO
Puurheid: ≥ 99%

Functions of Hordenine

Hordenine is primarily known for the possible stimulant effects of hordenine. Hordenine can also be considered as a substance that may have similar effects to nootropics [1][2][3][4][5][6][7].

Where does Hordenine come from ?

Hordenine can be found in a variety of plants and products. It is currently known that it can be found in: barley, bitter orange, algae, cacti, and some grass species [8][9][10]. Since it is found in barley, it can also be used to measure beer consumption [11]. This is possible since the hordenine level in our blood can increase after beer consumption [11].

References

1. Barwell, C. J., Basma, A. N., Lafi, M. A. K., & Leake, L. D. (1989). Deamination of hordenine by monoamine oxidase and its action on vasa deferentia of the rat. Journal of pharmacy and pharmacology, 41(6), 421-423.
2. Shih, J. C., Chen, K., & Ridd, M. J. (1999). Role of MAO A and B in neurotransmitter metabolism and behavior. Polish journal of pharmacology, 51(1), 25-29.
3. Hapke, H. J., & Strathmann, W. (1995). Pharmacological effects of hordenine. DTW. Deutsche Tierarztliche Wochenschrift, 102(6), 228-232.
4. Bloomer, R. J., Fisher-Wellman, K. H., Hammond, K. G., Schilling, B. K., Weber, A. A., & Cole, B. J. (2009). Dietary supplement increases plasma norepinephrine, lipolysis, and metabolic rate in resistance trained men. Journal of the International Society of Sports Nutrition, 6(1), 1-9.
5. Fišar, Z., Hroudová, J., & Raboch, J. (2010). Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers. Neuroendocrinology letters, 31(5), 645.
6. Kong, P., Zhang, B., Lei, P., Kong, X., Zhang, S., Li, D., & Zhang, Y. (2015). Neuroprotection of MAO-B inhibitor and dopamine agonist in Parkinson disease. International journal of clinical and experimental medicine, 8(1), 431.
7. Su, S., Cao, M., Wu, G., Long, Z., Cheng, X., Fan, J., … & Wang, X. (2018). Hordenine protects against hyperglycemia-associated renal complications in streptozotocin-induced diabetic mice. Biomedicine & Pharmacotherapy, 104, 315-324.
8. Pellati, F., & Benvenuti, S. (2007). Chromatographic and electrophoretic methods for the analysis of phenetylamine alkaloids in Citrus aurantium. Journal of Chromatography A, 1161(1-2), 71-88.
9. Mangino, M. M., & Scanlan, R. A. (1984). Rapid formation of N-nitrosodimethylamine from gramine, a naturally occurring precursor in barley malt. IARC scientific publications, (57), 337-346.
10. Wainwright, T., Slack, P. T., & Long, D. E. (1982). N-nitrosodimethylamine precursors in malt. IARC scientific publications, (41), 71-80.
11. Steiner, I., Brauers, G., Temme, O., & Daldrup, T. (2016). A sensitive method for the determination of hordenine in human serum by ESI+ UPLC-MS/MS for forensic toxicological applications. Analytical and bioanalytical chemistry, 408(9), 2285-2292.
12. Schweitzer, A., & Wright, S. (1938). Action of hordenine compounds on the central nervous system. The Journal of physiology, 92(4), 422.
13. Singh, A. K., Granley, K., Misrha, U., Naeem, K., White, T., & Jiang, Y. (1992). Screening and confirmation of drugs in urine: interference of hordenine with the immunoassays and thin layer chromatography methods. Forensic science international, 54(1), 9-22.